منابع مشابه
Effects of dextran 70 on hemodynamics and lung liquid and protein exchange in awake sheep.
We studied the effect of intravenous dextran 70 infusion on lung liquid and protein exchange to determine whether its effects were due to altered hemodynamics or to altered microvascular permeability. In each of six instrumented awake sheep with chronic lung lymph fistulas, we performed three experiments: 1) control, 2) a 30-minute infusion of 1 l of 6% dextran 70, and 3) an infusion of 1 l of ...
متن کاملAmelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB.
Butyrate enemas have been demonstrated to ameliorate inflammation in ulcerative colitis. The mechanism of this protective effect of butyrate is not known, and this study examines the effect of butyrate on epithelial function, inducible heat shock protein 70 (HSP70) expression, and NF-kappaB activation in experimental colitis. Colitis was induced in rats by oral dextran sulfate sodium (DSS) and ...
متن کاملPreparation and characterisation of Dextran-70 hydrogel for controlled release of praziquantel
A hydrogel was developed from 70 kDa dextran (DEX-70) and praziquantel (PZQ) incorporated as a model drug. Biopharmaceutical properties, such as solubility and dissolution rate, were analysed in the design of the hydrogel. Furthermore, the hydrogel was also characterized by IR spectroscopy and DSC. Tests of the swelling rate showed that the hydrogel swelled slowly, albeit faster than the rate f...
متن کاملImpact of Polyethylene Glycol and Dextran 70 Treatment on Adhesion Formation after Subtotal Thyroidectomy
Secondary thyroidectomy can be complicated due to adhesions. This study evaluates the impact of two antiadhesive barriers on adhesion formation after subtotal thyroidectomy in a rat model. Twenty-eight Wistar alb ino rats were randomized into three groups after subtotal thyroidectomy. Dextran 70 was used in Group 1 (n=10), Polyethylene glycol (PEG) was used in Group 2 (n =10), and the control g...
متن کاملInfluence of dextran-70 on systemic inflammatory response and myocardial ischaemia-reperfusion following cardiac operations
INTRODUCTION Experimental studies have demonstrated that dextran-70 reduces the leukocyte-endothelium interaction, but clinical evidence is still lacking. Our objective was to justify the anti-inflammatory effect of dextran-70 following cardiac operations. METHODS Forty patients undergoing coronary bypass surgery (n = 32) or aortic valve replacement (n = 8) were enrolled in this prospective, ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1975
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5971.614-c